姓  名:王明华
技术职称:副教授
导师类型:硕导
所在学系:生物化学与分子生物学系
学科专业:生物化学与分子生物学
研究方向

1.  基因表达与调控

2.  肿瘤药理学

3.  肿瘤分子遗传学

个人简历

1995.7大学毕业于西北大学生物系生物学专业,毕业后于陕西省教育学院生化系任教。

1997.9-2000.1于西北农林科技大学基础科学系攻读生物化学与分子生物学专业硕士学位,并获理学硕士。硕士学位论文工作在中国科学院北京微生物研究所遗传室完成。毕业后在上海第二医科大学上海市发育生物学重点实验室进修半年。

2001.9-2005.1于复旦大学遗传所攻读遗传学专业博士学位,并获理学博士。在遗传工程国家重点实验室从事博士学位论文工作。

2005.5月至今在苏州大学基础医学与生物科学学院生物化学与分子生物系从事教学科研工作。2007年被聘为副教授。

2010.3-2012.2在美国约翰霍普金斯大学医学院高级访问研究。
学术成果

1.Xu FQ, Wang WP, Lei C, Liu QM, Qiu H, Vinaydhar M, Zhou B, Cheng HX, Huang ZK, Xu WA, Li BC, Wang MH. Activation of transcriptional activity of HSE by a novel mouse zinc finger protein ZNFD specifically expressed in testis. Mol Cell Biochem. 2012 Jan 10. (Corresponding author)

2.Yang SR, Wang WP, Lei C, Liu QM, Xu FQ, Xing XW, Chen H, Liu JJ, Wu SL, Wang MH. Localization and characterization of rat transmembrane protein 225 specifically expressed in testis. DNA Cell Biol. 2011, 30: 9-16 (Corresponding author)

3.Liu QM, Yao F, Wang MH, Zhou B, Cheng HX, Wang WP, Jin L, Lin Q, Wang JC. Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRE. Mol Cell Biochem. 2011 Nov;357(1-2):405-14.

4.Lei C, Liu QM, Wang WP, Li J, Xu FQ, Liu YZ, Liu JJ, Wu SL, Wang MH. Isolation and characterization of a novel zinc finger gene, ZNFD, activating AP1(PMA) transcriptional activities. Mol Cell Biochem. 2010, 340: 63-71. (Corresponding author)

5.Wang JC, Wang MH, Zhang RM, Zhao ZM, Chen J, Luo ZW. A chemiluminescence-based assessment of androgen binding activity in a large pedigree affected with androgen insensitivity syndrome, Luminescence . 2007,22: 370–378

6.Wang MH, Luo GM, Li F, Wu SL, Jiang JX, Huang CQ. Isolation and Characterization of a Novel Four-Transmembrane Protein PMP22CD Specifically Expressed in the Testis. Int. J. Mol. Sci. 2006,7, 425-437

7.Wang MH, Wang JC, Zhang Z, Zhao ZM,Zhang RM, Hu XH, Tan T, Luo SJ, Luo ZW. Dissecting phenotypic variation among AIS patients. Biochem Biophys Res Commun. 2005,23;335(2):335-42.

8.Zhang HT, Chen XF, Wang MH, Wang JC, Qi QY, Zhang RM, Xu WQ, Fei QY, Wang F, Cheng QQ, Chen F, Zhu CS, Tao SH, Luo Z. Defective expression of transforming growth factor beta receptor type II is associated with CpG methylated promoter in primary non-small cell lung cancer. Clin Cancer Res. 2004, 1;10(7):2359-67.

9.Qi QY, Wang F, Zhang HT, Wang JC, Xiao HP, Wang MH, Han YF, Zhang RM, Tao SH, Luo ZW. Induced recovery of defective membrane expression of a CC chemokine receptor 5 mutant by phytohemagglutinin. Cell Mol Life Sci. 2003, 60(11):2492-500.

10.Fei QY, Zhang HT, Chen XF, Wang JC, Zhang RM, Xu WQ, Zhang Z, Zou W, Zhang KY, QI qy, Wang MH, Tao sh, Luo Zw. Defected expression of E-cadherin in non-small cell lung cancer. Lung Cancer. 2002,37:147-152
代表项目

国家自然科学基金(30700826)

苏大医学发展基金(EE134709)

国家自然科学基金(81071957)


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