姓  名:陶金
技术职称:教授、东吴学者
导师类型:博士生导师
所在学系:生理学与神经生物学系
学科专业:(医学)神经生物学
研究方向

1. 离子通道病

2. 偏头痛的发病机制

个人简历

2013.05 – 目前     苏州大学医学部生理学与神经生物学系,主任、教授、博导、东吴学者;苏州大学神经科学研究所PI

2009.06 –2013.05   苏州大学医学部神经生物学系,教授、东吴学者

2007.08 –2009.06   美国圣路易斯华盛顿大学医学院疼痛研究中心,博士后

2005.08 - 2007.07   新加坡国立大学/国家神经科学研究所,助理研究员

2002.09 - 2007.07   南京医科大学药理学系(NUS联合培养博士生),医学博士

1997.09 - 2002.06   南京医科大学临床医学系,医学学士
学术成果

1.         Guo Q, Jiang YJ, Jin H, Jiang XH, Gu B, Zhang YM, Wang JG, Qin ZH, Tao J*. Modulation of A-type K+ channels by the short-chain cobrotoxin through the protein kinase C-delta isoform decreases membrane excitability in dorsal root ganglion neurons. Biochem Pharmacol 2013, 85(9):1352-62.

2.         Zhang Y, Jiang X, Snutch TP, Tao J*. Modulation of low-voltage-activated T-type Ca² channels. Biochim Biophys Acta 2013, 1828(7):1550-9.

3.         Zhang Y, Jiang D, Zhang Y, Jiang X, Wang F, Tao J*. Neuromedin U type 1 receptor stimulation of A-type K+ current requires the βγ subunits of Go protein, protein kinase A, and extracellular signal-regulated kinase 1/2 (ERK1/2) in sensory neurons. J Biol Chem 2012, 287(22):18562-72.

4.         Zhang Y, Zhang J, Jiang D, Zhang D, Qian Z, Liu C, Tao J*. Inhibition of T-type Ca² channels by endostatin attenuates human glioblastoma cell proliferation and migration. Br J Pharmacol 2012, 166(4):1247-60.

5.         Zhang L, Zhang Y, Jiang D, Reid PF, Jiang X, Qin Z, Tao J*. Alpha-cobratoxin inhibits T-type calcium currents through muscarinic M4 receptor and Gο-protein βγ subunits-dependent protein kinase A pathway in dorsal root ganglion neurons. Neuropharmacology 2012, 62(2):1062-72.

6.         Zhang Y, Zhang L, Wang F, Zhang Y, Wang J, Qin Z, Jiang X, Tao J*. Activation of M3 muscarinic receptors inhibits T-type Ca2+ channel currents via pertussis toxin-sensitive novel protein kinase C pathway in small dorsal root ganglion neurons. Cell Signal 2011, 23: 1057-1067.

7.         Wang F, Zhang Y, Jiang X, Zhang Y, Zhang L, Gong S, Liu C, Zhou L, Tao J*. Neuromedin U inhibits T-type Ca2+ channel currents and decreases membrane excitability in small dorsal root ganglia neurons in mice. Cell Calcium 2011, 49, 12-22.

8.         Xu G, Wang F, Jiang X, Tao J*. Aquaporin 1, a potential therapeutic target for migraine with aura. Molecular Pain 2010, 6, 68-76. (Highly Accessed)

9.         Zhang Y, Jiang D, Zhang J, Wang F, Jiang X, Tao J*. Activation of neuromedin U type 1 receptor inhibits L-type Ca2+ channel currents via phosphatidylinositol 3-kinase-dependent protein kinase C epsilon pathway in mouse hippocampal neurons. Cell Signal 2010, 22, 1660-1668.

10.     Tao J*, Zhang Y, Huang H, Jiang X. Activation of corticotropin-releasing factor 2 receptor inhibits Purkinje neuron P-type calcium currents via Goα-dependent PKC eposilon pathway. Cell Signal 2009, 21, 1436-1443.

11.     Tao J, Hildebrand ME, Liao P, Liang MC, Tan G, Li S, Snutch TP, Soong TW. Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels. Mol Pharmacol 2008, 73, 1596-1609.

12.     Tao J, Zhang Y, Li S, Sun W, Soong TW. Tyrosine kinase-independent inhibition by genistein on spermatogenic T-type calcium channels attenuates mouse sperm motility and acrosome reaction. Cell Calcium 2009, 45, 133-143.

13.     Zhang Y, Tao J*, Huang H, Ding G, Cheng Y, Sun W. Effects of celecoxib on voltage-gated calcium channels in rat pheochromocytoma cells. Pharmacol Res 2007, 56, 267-274.

14.     Tao J, Zhang Y, Soong TW, Li S. Expression of urocortin 2 and its inhibitory effects on intracellular Ca2+ via L-type voltage-gated calcium channels in rat pheochromocytoma cells. Neuropsychopharmacology 2006, 31, 2600-2609.

15.   Tao J, Xu H, Yang C, Liu CN, Li S. Effect of Urocortin on L-type calcium currents in adult rat ventricular myocytes. Pharmacol Res 2004, 50, 471-476.

 

代表项目

1. 国家自然科学基金(81171056,主持,在研

2. 国家自然科学基金(NSFC-CNRS项目,81311130114,主持,在研

3. 国家自然科学基金(30900437,主持,已结题

4. 教育部留学回国人员启动基金,第40批,主持,在研

5. 江苏省自然科学基金,BK2011293,主持,在研

6. 江苏省高校自然科学基金, 09KJB180008,主持,已结题

7. 东吴学者计划资助,主持,在研
社会兼职
江苏省疼痛学会青年委员
其  他

教改及奖励:

1. 国家级大学生创新项目2项,导师

2. 江苏省大学生创新创业项目1项,导师

3. 苏州大学大学生课外学术科研基金重大项目1项,导师

4. 江苏省优秀多媒体课件二等奖,排名第一

5. 苏州大学医学部教改项目1项,主持

6.   江苏省科学技术奖三等奖,排名第三

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